Alexandre Bonvin bio photo

Computational Structural Biology group focusing on dissecting, understanding and predicting biomolecular interactions at the molecular level.

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PowerFit and DisVis tutorials

In this page you can find links and tutorials to two HADDOCK-complementary softwares DisVis and PowerFit. PowerFit focuses on fitting of atomic resolution structures of biomolecules to cryo-electron microscopy (cryo-EM) density maps. DisVis visualises and quantifies the information content of distance restraints between macromolecular complexes.

  • PowerFit tutorial: A small introduction into PowerFit to automatically place a high-resolution atomic structure in a lower-resolution cryo-electron microscopy density map.

  • PowerFit web server tutorial: A small introduction into PowerFit to automatically place a high-resolution atomic structure in a lower-resolution cryo-electron microscopy density map making use of our web portal (does not require Linux).

  • DisVis web server tutorial: A small introduction into DisVis to analyse the interaction space between two molecules from a set of restraints. It can help to filter out putative false positive restraints and predict key residues involved in the interaction from this set of restraints. It makes use of our web portal (does not require Linux).